Research Article
ISSN: 2572 4355

Childhood lymph node lymphoma in a developing community

Wilson Onuigbo
Department of Pathology, Medical Foundation & Clinic, 8 Nsukka Lane, Enugu, 400001 Nigeria
Corresponding author: Wilson Onuigbo
Department of Pathology, Medical Foundation & Clinic, 8 Nsukka Lane, Enugu, 400001 Nigeria. E-mail: wilson.onuigbo@gmail.com
Received Date: July 02,2018 Accepted Date: July 12,2018 Published Date: July 30,2018
Citation: Wilson Onuigbo. (2018), Childhood lymph node lymphoma in a developing community. Int J Ped & Neo Heal. 2:7, 84-85.
Copyright: ©2018 Wilson Onuigbo. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited


Before the ascendancy of the Internet in Scientific communication, there was a keen traffic in the reprint request (RR). As an Editor mentioned in 1986, “Onuigbo (was) the only active researcher that I have traced in the RR area.” Therefore, this paper on childhood utilizes reprints on malignant lymphoma but with the variable ages defined as “at most 14 years,” up “to 15 years,” “under 16 years,” “under age 17 years,” and “younger than 20 years.” In particular, I have used the number 20 to analyze cases occurring in a developing community using a histology data pool as was recommended in Birmingham (UK) for epidemiologic analysis. It was found that the age incidence preponderated in the older age groups with a 3:1 male:female ratio.

Keywords:  Childhood, lymph nodes, lymphoma, sex, Igbos, Nigeria.




Introduction


The requested reprint (RR) held sway in scientific communications before the Internet era. In this context, John Swales,1 Editor of English for Specific Purposes, concluded that I am “the only active researcher that I have traced in the RR area.” Incidentally, I possess 5 reprints on childhood lymphomas. It is of interest that the age limits varied as follows: (i) “at most 14 years,”2 (ii) up “to 15 years,”3 (iii) “under 16 years,”4 (iv) “under age 17 years,”5 and (v) “younger than 20 years.”6 A point of interest is that the above reprints came from Sweden, Saudi Arabia, Italy, USA, and Venezuela. Hence, a Nigerian source is well worth documentation. Therefore, for this paper, I have chosen 20 years as the upper limit. Moreover, I followed the recommendation of a Birmingham (UK) group that the establishment of a histopathology data pool facilitates epidemiological analysis.7 The catchment was the Ethnic Group called the Ibos or Igbos.8 The data were amassed in the Regional Pathology Laboratory established by the Government of the Eastern Region of Nigeria at the erstwhile Capital City, Enugu. Having kept a copy of the results personally, manual sorting has been undertaken. The documentation is presented in tabular form.

Results


ijpn Digital images
Table 1: shows the age-sex pattern.

It is apparent that, of the involved 42 children, most were in the older age groups. Furthermore, males preponderated in the ration of 3 to 1. It was of interest to find out also the lymph node situations. They preponderated in the neck with 28 cases followed by multiple sites in 25. Axillary, groin, and intraabdominal positions were few relatively. Another point of interest was the provisional diagnosis as was required in the Request Forms. There was the pleasant surprise of up to 27 correct diagnoses. Malignancy was the generalization in 6 other cases. Tuberculosis came next with distant 4 cases, while miscellaneous diagnoses included such lesions as lymphadenopathy and leukemia.

Discussion


Having concentrated on RR so far, what is there to learn further from recent Internet examples? In particular, the geographical spread should be of interest as was used above. Interesting informations were gathered from Germany,9 Australia,10 UK11 and Belgium.12 The data from USA added the historical origins of lymphoma as “swellings of lymph nodes that were unrelated to tuberculosis or to other recognized pathology in the drainage area of the lymph node group.”13 The epidemiological aspect that was closest to my local findings was provided from Sweden.14 There, the definite age was “younger than 15 years of age” while the male-female ratio was 4.1:1. The Igbo ratio came to 3:1.


References:

  1. Swales J. ESP in the big world of reprint requests. English for Specific Purposes, 1986; 5(1): 81-85.
  2. Garwicz S, Landberg T, Akerman M. Malignant lymphomas in children: A clinico-pathologic retrospective study. Acta Padiatr Scand, 1974; 63: 673-678.
  3. Bim-Ahmed OS, Sabbah RS. Childhood non-Hodgkin’s lymphoma in Saudi Arabia: Clinical features of 100 cases. King Faisal Specialist Hosp Med J. 1982; 2(4): 217-224.
  4. Gasparim M Fossati-Bellani F, Lombardi F, et al. Childhood non-Hodgkin malignant lymphomas: A clinicopathologic retrospective study. Med Pediat Oncol, 1979; 6: 243-253.
  5. Traggis D, Norman J, Vawter G, baez-Giangreco A. Non-Hodgkin lymphoma of the head and neck in childhood. J Padiat; 1975; 87(6): 933-936.
  6. Hausner RJ, Rosas-Uribe A, Wickstrum DA, Smith PC. Non-Hodgkin’s lymphoma in the first two decades of life: A pathological study of 30 cases. Cancer, 1977; 40(4): 1533-1547.
  7. Macartney JC, Rollaston TP, Codling BW. Use of a histopathology data pool for epidemiological analysis. J Clin Pathol 1980; 33: 351-353.
  8. Basden GT. Niger Ibos. Cass, London 1966.
  9. Rosolen A, Perkins SL, Pinkerton CR, et al. Revised international pediatric non-Hodgkin lymphoma staging system. J Clin Oncol, 2015; 33(18): 2112-2118.
  10. White L, Siegel SE, Quah TC. Non-Hodgkin’s lymphomas in children. II. Treatment. Oncol Hematol, 1992; 13(1): 73-89.
  11. Wright D, McKeever P, Carter R. Childhood non-Hodgkin lymphomas in the United Kingdom: Findings from the UK Children’s Cancer Study Group. J Clin Pathol, 1997; 50: 709-a.
  12. Minard-Colin V, Brugieres L, Reiter A, et al. Non-Hodgkin lymphoma in children and adolescents: Progress through effective collaboration, current knowledge, and challenges ahead. J Clin Oncol, 2015; 33(27): 2963-2974.
  13. Leventhal BG, Kato GJ. Childhood Hodgkin and non-Hodgkin lymphomas. Pediat Rev, 1990; 12(6): 171.
  14. Bengt SO, Borje R, Liselotte R, et al. Non-Hodgkin lymphoma in children: A 20-year population-based epidemiologic study in Western Sweden. J Pediat Hematol/Oncol, 1999; 21(2): 103-110

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